CXR

CXR’s collaborative and advisory approach, toxicological expertise and extensive laboratory capabilities have helped customers of all sizes resolve issues relating to the safety of compounds or selection of drug or chemical candidates.

Our customers include leading pharmaceutical, agrochemical, chemical, consumer product and biotechnology companies. We provide Investigative Toxicology, Exploratory & Discovery Toxicology, Metabolism &  PK/TK and Dermal Absorption services and expertise on a contract research basis.

CXR employs over 35 staff recruited from both industrial and academic backgrounds, over 30% of whom have PhDs. The combination of academic excellence together with extensive industrial experience in pharmaceutical, agrochemical and chemical toxicology, metabolism and pharmacokinetics leads to a uniquely skilled investigative toxicology and preclinical development service.

To date, we have helped over 60 companies/consortia of all sizes across a broad range of different sectors including global pharmaceutical, biotech, agrochemical, consumer product, industrial chemical and fine chemical companies. These have included: BASF, Bayer, Dow Agrochemical, DuPont, Monsanto, Syngenta, ExxonMobil, AstraZeneca, Sanofi-Aventis, Pfizer, Roche, Procter & Gamble, Cancer Research Technology, Ineos Fluor, Ineos Chlor, 3M, Plastics Europe and ECPI.

Services

Investigative and Mechanistic Toxicology

We design and perform experiments to explain observed toxicities, and evaluate the actual hazard and risk to humans…

Exploratory and Discovery Toxicology

We use mechanistic toxicology at the research stage to drive chemical design, candidate selection and translational risk assessment…

Metabolism and PK/TK Support

CXR works with agrochemical, chemical and pharmaceutical companies to generate PK/TK, absorption and metabolic profiling data…

Dermal absorption, metabolism and toxicity.

In vitro studies to predict human exposure, drive risk assessments and bioequivalence studies, and help select chemicals and formulations…

Industries

Agrochemical
Crop Protection

CXR has provided exploratory toxicology and investigative toxicology services to the agrochemical industry for many years.

Pharmaceutical & Biotech

CXR works with pharmaceutical and biotechnology companies to support discovery toxicology and investigative toxicology programs.

Chemical

CXR has provided investigative toxicology, metabolism, absorption and read-across services to the chemicals industry for many years.

Consumer products

CXR has expertise in elucidating potential mechanisms of toxicity of marketed consumer products, & of using primary cell culture and genomics to support product claims.

Latest News

CXR Biosciences gains GLP accreditation, launches in-vitro dermal absorption service following industry demand

29.06.16

CXR Biosciences, part of the Concept Life Sciences Group, has added in vitro dermal absorption studies to their already comprehensive portfolio of mechanistic toxicology and ADMET services.  This is also the first service that CXR offers to formal Good Laboratory Practice (GLP) standards, following a successful audit by the MHRA on 23rd June. The purpose […]

Royal Society - Kohn Centre 2

Concept Life Sciences Group Event Success: Early Safety and Enhancing the Discovery Process Spotlight, London, UK

05.05.16

Concept Life Sciences Group Event Success: Early Safety and Enhancing the Discovery Process Spotlight, London, UK 05/05/2016   CXR Biosciences and Peakdale Molecular (members of the Concept Life Sciences Group) brought together a number of eminent speakers recently as part of their Spotlight Session series. The event, which was held at the Kohn Centre at […]

New investigative toxicology research from CXR Biosciences: six posters to be co-presented at the upcoming Society of Toxicology conference in partnership with BASF, Adama, Monsanto and the H4R REACH consortium

04.03.16

CXR Biosciences, the investigative and exploratory toxicology company, is co-presenting six posters at the upcoming Society of Toxicology meeting in New Orleans on 13th – 17th March.  This innovative research has been performed with several CXR customers including BASF, Adama, Monsanto and the H4R REACH consortium. Four posters describe studies performed at CXR to investigate […]

CXR Biosciences wins overall Business of the Year, Science and Technology Business of the Year and Growth Business of the Year at The Courier Business Awards

30.11.15

An outstanding year for CXR Biosciences was recognised with a triple win at the 2015 Courier Business Awards, including becoming the third winner of the coveted Business of the Year prize at the glittering Courier Business Awards ceremony at the Fairmont St Andrews.

CXR Biosciences receives French Research Tax Credit accreditation

23.11.15

CXR Biosciences, the investigative and exploratory toxicology company, is pleased to announce that it has received French research tax credit approval for years 2015 through to 2017.

Concept Life Sciences makes its fifth acquisition further expanding its analytical support services

19.10.15

Concept Life Sciences, scientific laboratory and consultancy group has acquired pharmaceutical analytical testing business Agenda1 Analytical Services Ltd (Agenda 1). This marks its fifth acquisition since it was formed in July 2014.