CXR’s collaborative and advisory approach, toxicological expertise and extensive laboratory capabilities have helped customers of all sizes resolve issues relating to the safety of compounds or selection of drug or chemical candidates.
Our customers include leading pharmaceutical, agrochemical, chemical, consumer product and biotechnology companies. We provide Investigative Toxicology, Exploratory & Discovery Toxicology, Metabolism & PK/TK and Dermal Absorption services and expertise on a contract research basis.
CXR employs over 35 staff recruited from both industrial and academic backgrounds, over 30% of whom have PhDs. The combination of academic excellence together with extensive industrial experience in pharmaceutical, agrochemical and chemical toxicology, metabolism and pharmacokinetics leads to a uniquely skilled investigative toxicology and preclinical development service.
To date, we have helped over 60 companies/consortia of all sizes across a broad range of different sectors including global pharmaceutical, biotech, agrochemical, consumer product, industrial chemical and fine chemical companies. These have included: BASF, Bayer, Dow Agrochemical, DuPont, Monsanto, Syngenta, ExxonMobil, AstraZeneca, Sanofi-Aventis, Pfizer, Roche, Procter & Gamble, Cancer Research Technology, Ineos Fluor, Ineos Chlor, 3M, Plastics Europe and ECPI.
Investigative and Mechanistic Toxicology
We design and perform experiments to explain observed toxicities, and evaluate the actual hazard and risk to humans…
Exploratory and Discovery Toxicology
We use mechanistic toxicology at the research stage to drive chemical design, candidate selection and translational risk assessment…
Metabolism and PK/TK Support
CXR works with agrochemical, chemical and pharmaceutical companies to generate PK/TK, absorption and metabolic profiling data…
CXR has provided exploratory toxicology and investigative toxicology services to the agrochemical industry for many years.
Pharmaceutical & Biotech
CXR works with pharmaceutical and biotechnology companies to support discovery toxicology and investigative toxicology programs.
CXR has provided investigative toxicology, metabolism, absorption and read-across services to the chemicals industry for many years.
CXR has expertise in elucidating potential mechanisms of toxicity of marketed consumer products, & of using primary cell culture and genomics to support product claims.
CONCEPT LIFE SCIENCES (FORMERLY CXR BIOSCIENCES) CO-AUTHORS TWO POSTERS DESCRIBING MODE OF ACTION STUDIES AT THE SOCIETY OF TOXICOLOGY 2017 ANNUAL MEETING
Research carried out at Concept Life Sciences (formerly CXR Biosciences), the investigative & exploratory toxicology company, is being presented in two posters at the upcoming Society Of Toxicology (SOT) 2017 annual meeting in Baltimore on 12th – 16th March. This mechanistic research has been performed in partnership with Endura SpA, Science Strategies LLC and Honeywell. […]
CONCEPT LIFE SCIENCES GROUP ANNOUNCES MULTIMILLION POUND EXPANSION PROGRAMME AND REBRANDING
Concept Life Sciences Group, the business formed in 2014 to break into the international Discovery & Development and Analytical markets, has announced its intention to significantly increase its investment in laboratory capacity and scientific staff. Michael Fort, Concept’s Executive Chairman said “The last two years has seen our company successfully integrate its acquired businesses and […]
CXR Biosciences crowned ‘Science and Technology Business of the Year’ for the second year running
CXR Biosciences, part of the Concept Life Sciences Group, has been crowned winner of the ‘Science and Technology Business of the Year’ award at The Courier Business Awards for the second year running. The award was presented to the company on Saturday 29th October at an official awards ceremony which was held at The Apex […]
CXR Biosciences to expand its mechanistic toxicology services following Scientific Advisory Board endorsement
CXR Biosciences, part of the Concept Life Sciences Group, held its second Scientific Advisory Board recently which focused on the mechanistic toxicology services required by the agrochemical, chemical, pharmaceutical and consumer products industries. CXR brought together experienced investigative toxicologists from across the various target industries to debate industry needs and emerging trends and how CXR […]
Cliff Elcombe, an Obituary
CLIFF ELCOMBE OBITUARY Dr Cliff Elcombe was a well-known and accomplished British toxicologist, who spent almost his entire career investigating the mechanisms of toxicity of various industrial chemicals and agrochemicals. He had an enviable reputation for his knowledge of, and insight into, non-genotoxic mechanisms of carcinogenesis and was internationally recognized for his work in predicting […]
It is with great sadness that we learned that our colleague Dr Cliff Elcombe died suddenly last Thursday, 25th August after a short illness. Cliff was co-founder and Research Director of CXR, and an internationally renowned toxicologist. Cliff played a huge role in the formation and success of CXR, as well as in the wider […]