Endocrine Disruption

Regulatory agencies are increasingly concerned about the potential for pesticides and other chemicals to act as endocrine disruptors.

Evidence suggests that the endocrine systems of certain fish and wildlife have been affected by chemical contaminants, resulting in developmental and reproductive problems.  It is therefore suggested that novel chemicals (and those due for re-registration) are tested for their potential to disrupt the human and animal estrogen, androgen and thyroid hormone systems.

CXR has extensive experience of assessing the potential for chemicals to disrupt the endocrine system through in vitro assays.  Should the potential for endocrine disruption be observed in a regulatory toxicology study or in vitro assay, CXR can design an investigative experimental programme to assess the effect of the compound on the endocrine system and determine the potential risk to humans.

Thyroid Hormone Endocrine Disruption case study

A case study is presented on page 6 of our Investigative Toxicology brochure.

For further information about our investigative endocrine disruption services, or to discuss a specific issue, please contact us.