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Founders

Professor Roland Wolf  FRSE, FMed Sci, FSA

Professor Roland Wolf is a co-founder of CXR Biosciences, Director of the University of Dundee Biomedical Research Centre, and Honorary Director of the Cancer Research UK Molecular Pharmacology Unit.  His research interests include understanding the pathways which determine the sensitivity of cells to drugs, environmental agents and chemical toxins, in particular, the application of molecular and genetic studies to determine how chemical agents interact with cells, how this influences their therapeutic and toxicological properties and how genetic polymorphisms in the genes involved relate to disease susceptibility, adverse drug pharmacology and toxicology.  Professor Wolf has published over 350 papers in peer-reviewed scientific journals and has received many awards, including the Gerhard Zbinden Award for contributions to the area of drug and chemical safety.

Dr Cliff Elcombe

Dr Cliff Elcombe as well as being co-founder and Technical Director of CXR Biosciences, is currently a Senior Lecturer in the Biomedical Research Centre, University of Dundee Medical School. Prior to starting CXR, Cliff joined the University of Dundee in February 1997 after an 18-year career at Zeneca's (formerly Imperial Chemical Industries) Central Toxicology Laboratory in Cheshire, England, where he was a Senior Scientist in Investigative Toxicology.

Dr. Elcombe’s research interests are focused on understanding mechanisms of target organ toxicity thereby facilitating scientifically-based risk assessment. Dr. Elcombe received his BSc and PhD in biochemistry from the University of Surrey and was awarded the European Society of Toxicology's young scientist award in 1984.

Dr Elcombe is the author or co-author of over 100 peer-reviewed publications and has served on several national and international advisory committees. At present he is an Independent toxicology member of the UK Advisory Committee on Pesticides.

 

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