Investigative & Mechanistic ToxicologyBy understanding the pathways that define the sensitivity of cells to chemicals, we evaluate the actual hazard to man - We have extensive experience in evaluating toxicological processes across species, and determining the relevance to man of observed adverse reactions to the satisfaction of regulatory bodies.
- Using this approach, we have ‘rescued’ compounds that may otherwise have been abandoned by industry.
- CXR will work with you to design state of the art investigative safety studies to understand the mechanisms of adverse preclinical observations, interpret the results and, if required, make recommendations as to the future of the project.
- We can prepare the documentation required for product support and accreditation (e.g. REACH).
- CXR also develops and applies new technologies for safety evaluation.
 Download the Investigative Toxicology brochure here
Further Information
Microarray services.
Using our microarray capabilities alongside other applied preclinical and toxicological approaches allows us to unravel complex mechanisms of toxicity and to establish their relevance to man. As the longest-standing Agilent-accredited microarray service provider in the UK, we supply the flexibility and expertise you require from your array service partner.
The AREc32 cell line
This is a screen for skin sensitisers and potential in vitro alternative to the Local Lymph Node Assay.
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