Hits to optimised leads

CXR Biosciences has extensive experience in the design of customised cost effective ADME/ tox packages that are tailored to suit individual requirements.  Constant communication with real time supply of data, and expert interpretation, together with flexible and responsive working practices makes CXR Biosciences a virtual arm of the sponsors’ drug discovery team.

Hits to Optimised lead programmes adopt a flexible yet structured approach, as the program of work is designed and implemented iteratively with each client.

The range of programme options can accommodate everything from ranking hundreds of compounds for selection, to more fully characterising a limited number of compounds to select the optimal lead.

Specific questions that can be addressed include:

Which of my compounds are bioavailable?  CXR Solution...

Which of my compounds have toxic liabilities? CXR Solution...

Will my compounds induce adverse drug reactions? CXR Solution...

Will my compounds interact with other medicines? CXR Solution...

What will be the likely variation in patient response? CXR Solution...

Do my compounds generate reactive metabolites ? CXR Solution